Sunday, December 6, 2015

FIRST PEOPLES RE-CULTURING OF GLOBAL HUMANITY


Vision/Purpose
To lead in the Global WHOLE-istic Re-culturing of Humanity via a First People’s model begun in a select North America Indian Nation based first on the development of a MutiCoRelational (Multilingual/Multicultural) Indigenous University which would then provide the innovation foundation to grow the Nation, e.g. into an international Intelligent Community Forum candidate as a notice to the World of the birthing of a New Relational Age born of the ancient traditions of all Indigenous People expressed in the Lakota aphorism, “mitakuye oyasin” (we are all related).

 Mission/Strategic Approach
To focus on the Democratization of Access to Knowledge and Capital, both individually and collectively, through SmartR Technology in Enterprise Development with an initial concentration on Education, Research, Entrepreneurial Technology Development & Business Applications. The SmartR Technology is PTI’s licensed AutoGnomicsTM [i.e. Self-Knowing] Knowledge Technologies.  Knowledge-itself is taken to be the fundamental value when Truthful, Relevant, and Collectively Good for Humanity. The initial applications focus is on the HealthCare and  Environmental Restoration Industries.

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PTI’s General Process
Precision: decisions driven by the best available knowledge
Therapeutics: actions directed towards enhancing humanity’s wellbeing in life &    environment
Innovation: ideation (conception), incubation (gestation), introduction (birthing)
& investment (nurturing) in entrepreneurial/enterprise development
PTI's Initial Knowledge Focus
A.   BioPhysical/BioChemical Life Components
B.   Precellular/Cellular Life Organization and Processes
C.   Mind/Body InterRelations and Synthetic Intelligence/Mind Applications
PTI’s Startup Application Focus Candidate
Empowering Innovators in Complex Carbohydrate Chemistry for Diabetes Therapeusis and Oxygen Supplementation

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BACKGROUND
First Peoples throughout the world face persistent challenges in community and economic development while protecting and growing their multi-lingual/multi-cultural distinctions and sovereign nation status while successfully interfacing with the broader non-indigenous world community. In order to compete and collaborate successfully, First Peoples must create new best practices in both business and government which begins from a recognition of their distinct cultures’ assets.

Every cultural tradition integrates ideas about ultimate existence (ChaotiCosmology) with ideas about which experiences ultimately matter (Ethics/Morality & Aesthetics). Recognizing that there is an accelerating growth in the awareness of the limits of the Systemic (thing-based, reductionist or mechanistic) Western Scientific Worldview, it is becoming ever more urgent for the sustainability of humanity to turn to a parallel focus emphasizing the necessity of a Relational Natural Worldview as the future. If the manifest Universe is relational, however, it behooves us to understand how relations relate! With this realization there comes the need to foundationally re-formulate the standard historical notion of “relation” which throughout recorded history has never addressed the possibility of MultiCoRelational forms. [The creation of MultiCoRelationalism has been introduced beginning in the period from 1963 to 1978 and is continuing at an exponentially growing pace]. The central challenge of the twenty-first century will be to integrate a (R)Evolutionary ChaotiCosmology with an Ecocentric Morality. An approach seems to be forming around the Epic of a CoCreative ChaotiCosmic (R)Evolution emerging from the necessarily irreducible Felt-Thought interrelation of the Analytical (Inquiry and Inference) and Intuitive modes of MIND as a System-as-WHOLE (metaphorically in the HoloGraphic sense). But since a Whole is No-Thing it requires interrelated relations for its explication. Hence the Relational Natural Worldview is that of a Universe as WHOLE and the (R)Evolution in Humanity is toward a societal organization in which each person is as the Whole. Toward that end, the principles of cooperative/collaborative organization are fundamental.

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NATIVE SCIENCE
In Native science, all relations are related to other relations. Native people have traditionally understood that creativity manifests itself in many ways, and that this creativity leads to new knowledge and a greater understanding of relations. The significance of the Lakota aphorism, "mitakuye oyasin" stems from the fact that it is a guiding principle of the "spiritual ecology" held by every tribe in its perception of nature. Guided by this metaphysical principle, people understood that all entities of nature—plants, animals, stones, trees, mountains, rivers, lakes, and a host of other living entities— embodied relations that must be honored. Through the seeking, making, sharing, and celebrating of these natural relations, they learned the subtle, but all important, language of relations. It was through such a mind-set over thousands of years, that Indigenous people accumulated their ecological knowledge and Relational Worldview.
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AUTOGNOMIC HEALTHCARE APPLICATION
The rapid emergence of Crowdsourced Knowledge Development including Citizen Science now has a focus on Crowdsourcing Clinical Trials (CCT). CCT expands the potential use of crowdsourcing from observational studies by adding it to truly randomized interventional trials. Randomized experiments allow causal inference because they assign subjects to a treatment and control group, and collect data from each. However, the fact that much of public health is driven by lifestyle factors suggests that CCT’s platform for crowdsourcing also has great potential to engage the public in producing new and trustworthy knowledge in the domains of diet, exercise, nutritional supplements, and integrative medicine, which are primary drivers of health outcomes and spending. This adds critical information so patients may make informed decisions. Such CCT problems are best addressed by a diverse yet cohesive community that can bring to bear the various perspectives, knowledge, experience, insights, and sheer volume of collective effort necessary to finding reasonable solutions.  The grand challenge for such collective intelligence is enabling and encouraging a simple crowd to become such a community, and to actively and coherently work on such problems, producing outcomes that are valuable both inside and outside the community. However, for many modern problems as with CCT, the availability of people who would make up such an effective community requires a distributed and asynchronous mediation. Approaches to logic, representation, and technology found in typical information technology applications, primarily oriented on representing settled data/facts about objects and events in the “outer world”, are generally not very effective in representing the dynamic “inner world” of emergent, often inconsistent thoughts and reasoning of individuals or communities. The AutoGnome provides a generalized, computer composable framework for relating experience (both past and anticipated) and knowledge consistent with contemporary embodied and ecological approaches to mind. Since AutoGnomics employs the same formal/semiotic framework for organizing and representing both personal and communal collective intelligence, it should be particularly effective in integrating with and enhancing both collective and individual intelligence in advancing CCT to AutoGnomic Community-sourced Critical Trials.

COMMUNITY-SOURCED CLINICAL TRIALS


INTELLISITE APPLICATION:
(9-1-15)

 CROWDSOURCING CLINICAL TRIALS (CCT): Edited excerpts from
http://www.minnesotalawreview.org/wp-content/uploads/2014/06/Sarpatwarietal._MLR1.pdf



The rapid emergence of Crowdsourced Knowledge Development including Citizen Science now has a focus on Crowdsourcing Clinical Trials (CCT). CCT expands the potential use of crowdsourcing from observational studies by adding it to truly randomized interventional trials. Randomized experiments allow causal inference because they assign subjects to a treatment and control group, and collect data from each. However, the fact that much of public health is driven not by pharmaceuticals, but by lifestyle factors suggests that CCT’s platform for crowdsourcing also has great potential to engage the public in producing new and trustworthy knowledge in the domains of diet, exercise, nutritional supplements, and integrative medicine, which are primary drivers of health outcomes and spending. This adds critical information to the technical, clinical, legal and ethical data as to whether all material information is provided so patients may make informed decisions. 

Such CCT problems are best addressed by a diverse yet cohesive community that can bring to bear the various perspectives, knowledge, experience, insights, and sheer volume of collective effort necessary to finding reasonable solutions. The grand challenge for such collective intelligence is enabling and encouraging a simple crowd to become such a community, and to actively and coherently work on such problems, producing outcomes that are valuable both inside and outside the community.

However, for many modern problems as with CCT, the availability of people who would make up such an effective community requires a distributed and asynchronous mediation. Approaches to logic, representation, and technology found in typical information technology applications, primarily oriented on representing settled data/facts about objects and events in the “outer world”, are generally not very effective in representing the dynamic “inner world” of emergent, often inconsistent thoughts and reasoning of individuals or communities. 

Enter the AUTOGNOME as a crowd-changing radical solution.

AUTOGNOMIC COMMUNITY-SOURCED CLINICAL TRIALS 
The AutoGnomic logic of Inquiry and Inference defines and combines three forms of argument—inductive, deductive, and abductive—into an iterative adaptive system for settling on outcomes in communities of inquiry that seek “concrete reasonableness” in complex environments. The AutoGnome, founded on Peirce’s theory of signs, or semiotics, is a comprehensive theory of representation of feeling, facts, and ideas in which reasoning in both individual and communal forms can be formally described. Peirce's theory is historically exceptional in involving a genuine triadic relation between sign, object, and interpretant—the latter critical to explicitly accounting for different perspectives in members of the community. In other words, a sign is formally a sign for someother   to  someone. The AutoGnome provides a generalized, computer composable framework for relating experience (both past and anticipated) and knowledge consistent with contemporary embodied and ecological approaches to mind. Since AutoGnomics employs the same formal/semiotic framework for organizing and representing both personal and communal collective intelligence, it should be particularly effective in integrating with and enhancing both collective and individual intelligence in advancing CCT to AutoGnomic Community-sourced Clinical Trials.